|
KMID : 1151820190130050811
|
|
Journal of the Korean Society of Radiology
2019 Volume.13 No. 5 p.811 ~ p.817
|
|
|
Efficiency Evaluation of Irradiated on Mouse Calvarial Model by BMP-2
|
|
Jung Hong-Moon
|
|
|
Abstract
|
|
|
|
Radiation-therapy causes the adverse radiation effect. It is called osteoradionecrosis. A protein-therapy is carried out in order to cure osteoradionecrosis. The typical method of the protein-therapy is using BMP-2. Considering to bone damage, it is more important that maintains enough to circumstance regeneration for osteoblast differentiation on damage site of bone. Thus, this study is on a tissue regeneration to cure radiation critical damage. I observed that the formation of new regeneration bone by injection of collagen sheet BMP-2 on irradiated mouse. Consequently, I examined new bone formation with collagen sheet BMP-2 on irradiated mouse after 8weeks. Therefore I suggested that using collagen sheet BMP-2 which can be good for new bone regeneration effect on radiation side effect area.
|
|
|
KEYWORD
|
|
|
irradiated mouse head, radiation bone damage, bone morphogenic protein-2, osteoradionecrosis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|